Horme

Collagen + Vitamin C

Emerging evidence for connective tissue, not for muscle.

  • Tier C — Preliminary or mixed — it might work, it might not
  • Health

What it is for

Possible support for tendons, ligaments and connective tissue.

How it works

It provides glycine/proline; with vitamin C it may stimulate collagen synthesis in connective tissue.

Dosing

15–30 g/day with vitamin C and loading exercise has been studied. This is a research range, not a universal prescription for treating an injury.

When to take it

Some protocols administer it before loading exercise. Taking it 30–60 minutes beforehand has not been established as optimal and does not replace rehabilitation.

Safety

Safe.

Side effects

Rare digestive discomfort.

Interactions

None relevant.

Contraindications

None in healthy people.

Who it has been studied in

Of interest for tendon/ligament injuries and rehabilitation.

Frequently asked

Is it useful for muscle?

It is a low-quality protein for stimulating muscle synthesis and does not replace complete sources. The 2026 review found no additional strength benefit from collagen; muscle-size results remain uncertain.

Evidence tier
C
Quality
Low-moderate
Studies
A few promising RCTs
Consensus
Emerging
Controversy
How much actually reaches the tendon? Debated
Reviewed
2026

Strength of evidence out of 5.

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